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VENDAJE
Vendaje is a Human Connective Tissue Matrix Comprised of Amniotic Tissue which is processed using our proprietary BioRetain process.
This process creates a dehydrated human amniotic membrane (DHAM) allograft.
BioRetain®-the science of letting nature do its work.
VENDAJE is intended for homologous use as a protective covering.
Easy to Use—Easy to Store
VENDAJE allografts:
– are held in place via hydrostatic tension and may be used in an open incision or placed as a dermal substitute.
– are aseptically processed and terminally sterilized via e-beam irradiation.
– have a 5-year shelf life and can be stored at ambient temperatures.
Six steps work together to preserve the natural integrity of amniotic tissue:
A LOOK INSIDE VENDAJE
Natural Amniotic Components Retained in VENDAJE
VENDAJE allografts are prepared using our proprietary BioRetain® process, which was designed to help preserve the natural ECM components, anti-inflammatory cytokines, and endogenous growth factors within fresh tissue.
The following substances were isolated within VENDAJE allografts (n=6)*:
Anti-inflammatory cytokines:
– Interleukin (IL) 10
IL-10 helps suppress the pro-inflammatory milieu and modulate immunity through a variety of pathways.
– IL-1 receptor antagonist
This substance naturally inhibits pro-inflammatory effects of IL-1.
Extracellular matrix (ECM) components:
– Collagens I, III, IV, V, and VI
– Elastin
– Laminin
– Fibronectin
– Proteoglycans
The ECM of amniotic membrane provides mechanical protection and functional support for cell attachment, proliferation, and migration.
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